Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2549070 | 0.81 | DRD4 (0.40) | ALDH1A1TP53MAPTTSHRMEN1 | |
| SCHEMBL31399939 | 0.75 | TSHR (0.46) | ALDH1A1TP53MAPTTSHRMEN1 | |
| SCHEMBL1013139 | 0.73 | TSHR (0.53) | ALDH1A1TP53MAPTTSHRMEN1 | |
| SCHEMBL11567488 | 0.70 | HTR6 (0.37) | HTR6 | |
| SCHEMBL2544497 | 0.69 | GAA (0.41) | ALDH1A1TP53MAPTTSHRMEN1 | |
| SCHEMBL24688441 | 0.67 | SIGMAR1 (0.41) | HTR6 | |
| SCHEMBL19707449 | 0.67 | SIGMAR1 (0.41) | HTR6 | |
| SCHEMBL14086792 | 0.64 | — | — | |
| SCHEMBL772391 | 0.64 | — | — | |
| SCHEMBL12717639 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011122815-A2 | NOVEL QUINOXALINE DERIVATIVES | DONG-A PHARM.CO.,LTD. (KR) | 2011-10-06 | — | — | WO | disclosed |