Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2548100 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TP53MAPTKMT2ATSHR | |
| SCHEMBL2544497 | 0.81 | GAA (0.41) | DRD4ALDH1A1TP53MAPTKMT2A | |
| SCHEMBL31399939 | 0.76 | TSHR (0.46) | ALDH1A1TP53MAPTKMT2ATSHR | |
| SCHEMBL1013139 | 0.74 | TSHR (0.53) | ALDH1A1TP53MAPTKMT2ATSHR | |
| SCHEMBL13252478 | 0.63 | ALDH1A1 (0.50) | ALDH1A1TP53MAPTKMT2ATSHR | |
| SCHEMBL18377696 | 0.63 | DRD4 (0.43) | DRD4ALDH1A1KMT2ADRD2DRD3 | |
| SCHEMBL19148006 | 0.63 | GAA (0.45) | DRD4ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL12337433 | 0.62 | IDO1 (0.38) | ALDH1A1KMT2AMEN1DRD2SMN1; SMN2 | |
| SCHEMBL6921678 | 0.62 | SMN1; SMN2 (0.48) | KMT2ASMN1; SMN2 | |
| SCHEMBL22819552 | 0.62 | SMN1; SMN2 (0.48) | KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011122815-A2 | NOVEL QUINOXALINE DERIVATIVES | DONG-A PHARM.CO.,LTD. (KR) | 2011-10-06 | — | — | WO | disclosed |