SCHEMBL2548346

SCHEMBL2548346

C=C[SiH2]C(OCCC)OCCC

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL557068 0.86 TSHR (0.36)
SCHEMBL7935124 0.85 DNM1 (0.39)
SCHEMBL7937310 0.83 DNM1 (0.42)
SCHEMBL339299 0.80 THRB (0.36)
SCHEMBL4090948 0.78
SCHEMBL4079093 0.76
SCHEMBL4083692 0.72
SCHEMBL4083701 0.69
SCHEMBL4090956 0.68
SCHEMBL3679767 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150132518-A1 CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2015-05-14 US claimed
CN-102858821-B Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom MOMENTIVE PERFORMANCE MAT INC 2015-04-22 CN claimed
US-8962718-B2 Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-02-24 US claimed
EP-2563827-A1 CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM Momentive Performance Materials Inc. (US) 2013-03-06 EP claimed
CN-102858821-A Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom MOMENTIVE PERFORMANCE MAT INC 2013-01-02 CN claimed
WO-2011139635-A1 CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-11-10 WO claimed
US-20110259464-A1 CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-10-27 US claimed
US-9988518-B2 Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-06-05 US disclosed
EP-2563827-B1 CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2017-06-21 EP disclosed
US-20150132518-A1 CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2015-05-14 US disclosed
CN-102858821-B Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom MOMENTIVE PERFORMANCE MAT INC 2015-04-22 CN disclosed
US-8962718-B2 Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-02-24 US disclosed
US-20130345370-A1 SILICONE RESIN COMPOSITION NITTO DENKO CORPORATION (JP) 2013-12-26 US disclosed
US-4867923-A FORMING SHAPED ARTICLE FROM THERMOPLASTIC RESIN, HYDROLYZABLE SILANE, GAS FORMER, PEROXIDE COMPOSITION, HEATING TO CURE AND FOAM UNION CARBIDE CORPORATION (US) 1989-09-19 US disclosed
EP-0207135-B1 OLEFIN POLYMER FOAMS UNION CARBIDE CORPORATION (US) 1989-04-05 EP disclosed
EP-0207135-A1 OLEFIN POLYMER FOAMS. UNION CARBIDE CORP (US) 1987-01-07 EP disclosed
WO-1986003759-A1 OLEFIN POLYMER FOAMS UNION CARBIDE CORPORATION (US) 1986-07-03 WO disclosed
US-4598116-A EXTRUSION COATING WIRES AND CABLES UNION CARBIDE CORPORATION (US) 1986-07-01 US disclosed
EP-0184674-A2 Scorch resistant compositions based on water-curable thermoplastic polymers having hydrolyzable, pendant silane moieties, and organo titanates UNION CARBIDE CORPORATION (US) 1986-06-18 EP disclosed
US-4593072-A Containing a silanol compound UNION CARBIDE CORPORATION (US) 1986-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130345370-A1 SILICONE RESIN COMPOSITION SEM1, SSRP1, CAD HSD17B10 2876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.