SCHEMBL7937310

SCHEMBL7937310

C=C[SiH2]C(OCCCCCC)OCCCCCC

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.42
TSHR P16473 2/20 0.37
ALDH1A1 P00352 1/20 0.35
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
RECQL P46063 2/20 0.34
GLA P06280 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
EPHX2 P34913 1/20 0.34
BLM P54132 1/20 0.34
LPAR1 Q92633 4/20 0.33
LPAR3 Q9UBY5 4/20 0.33
LPAR2 Q9HBW0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7935124 0.98 DNM1 (0.39) DNM1TSHRALDH1A1CNR1CNR2
SCHEMBL557068 0.92 TSHR (0.36) DNM1TSHRALDH1A1CNR1CNR2
SCHEMBL2548346 0.83 HSD17B10 (0.30)
SCHEMBL339299 0.73 THRB (0.36)
SCHEMBL10071568 0.72 DNM1 (0.47) DNM1TSHRALDH1A1CNR1CNR2
SCHEMBL19792764 0.72 DNM1 (0.47) DNM1TSHRALDH1A1CNR1CNR2
SCHEMBL11010126 0.72 DNM1 (0.47) DNM1TSHRALDH1A1CNR1CNR2
SCHEMBL2623215 0.72 DNM1 (0.47) DNM1TSHRALDH1A1CNR1CNR2
SCHEMBL4090915 0.72 DNM1 (0.33) DNM1TSHRALDH1A1CNR1CNR2
SCHEMBL10494286 0.71 DNM1 (0.45) DNM1TSHRALDH1A1CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112585248-B Sliding material composition, sliding molded article, and sliding member 理研科技株式会社 2023-02-28 CN disclosed
US-11370986-B2 Sliding material composition, sliding molded article, and sliding member RIKEN TECHNOS CORPORATION (JP) 2022-06-28 US disclosed
CN-109790339-B Elastomer composition, water-crosslinkable elastomer composition, and method for producing same 理研科技株式会社 2022-06-14 CN disclosed
US-20210324286-A1 SLIDING MATERIAL COMPOSITION, SLIDING MOLDED ARTICLE, AND SLIDING MEMBER RIKEN TECHNOS CORPORATION (JP) 2021-10-21 US disclosed
US-6232376-B1 BLEND CONTAINING ORGANOSILICON COMPOUND, PEROXIDE, HINDERED AMINE STABILIZER AND ANTIOXIDANTS NIPPON UNICAR COMPANY LTD. (JP) 2001-05-15 US disclosed
EP-0135923-B1 PRODUCTION OF WATER-CURABLE, SILANE MODIFIED THERMOPLASTIC POLYMERS UNION CARBIDE CORPORATION (US) 1989-09-20 EP disclosed
US-4767820-A HYDROLYZABLE, PENDANT SILANE MOIETIES ON HOMO- OR COPOLYMER OF AN OLEFIN OR DIOLEFIN UNION CARBIDE CORPORATION (US) 1988-08-30 US disclosed
US-4753993-A WATER CURABLE ETHYLENE POLYMERS HAVING PENDANT HYDROLZABLE SILANE GROUPS UNION CARBIDE CORPORATION (US) 1988-06-28 US disclosed
US-4707520-A Composition based on water-curable thermoplastic polymers and metal carboxylate silanol condensation catalysts UNION CARBIDE CORPORATION (US) 1987-11-17 US disclosed
EP-0212630-A2 Compositions based on water-curable thermoplastic polymers and metal carboxylate silanol condensation catalysts UNION CARBIDE CORPORATION (US) 1987-03-04 EP disclosed
US-4579913-A Composition of a relatively stable polymer of an olefinic monomer and an unsaturated silane, and an organo titanate UNION CARBIDE CORPORATION (US) 1986-04-01 US disclosed
US-4526930-A Contains organotitanate for ester exchange UNION CARBIDE CORPORATION (US) 1985-07-02 US disclosed