Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MMP2 | P08253 | 3/20 | 0.55 |
| ▸ | MMP3 | P08254 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | AGER | Q15109 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30102507 | 1.00 | LMNA (0.60) | LMNAALDH1A1HPGDMMP2MMP3 | |
| SCHEMBL29113764 | 1.00 | LMNA (0.60) | LMNAALDH1A1HPGDMMP2MMP3 | |
| SCHEMBL10708127 | 0.95 | ALDH1A1 (0.66) | LMNAALDH1A1HPGDMMP2MMP3 | |
| SCHEMBL5949941 | 0.85 | LMNA (0.78) | LMNAALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL868642 | 0.84 | MMP2 (0.54) | LMNAALDH1A1HPGDMMP2MMP3 | |
| SCHEMBL6110358 | 0.84 | ALDH1A1 (0.66) | LMNAALDH1A1HPGDMMP2MMP3 | |
| Cyanate SCHEMBL27852686 | 0.83 | MMP2 (0.54) | LMNAALDH1A1HPGDMMP2MMP3 | |
| SCHEMBL10420085 | 0.81 | ALDH1A1 (0.63) | LMNAALDH1A1HPGDMMP2MMP3 | |
| SCHEMBL10701283 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HPGDMMP2MMP3MAPT | |
| SCHEMBL16450860 | 0.81 | ALDH1A1 (0.63) | LMNAALDH1A1HPGDMMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295149-A1 | MONOBACTAM COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS | NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) | 2023-09-21 | — | — | US | disclosed |
| US-20230150996-A1 | B-LACTAM COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS | NINGXIA ACADEMY OF AGRICULTURE AND FORESTRY SCIENCES (CN) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150996-A1 | B-LACTAM COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS | LBR, MRPL21, MRPL19 | LMNA 197/4885ALDH1A1 3531/4885HPGD 2557/4885 |
| US-20230295149-A1 | MONOBACTAM COMPOUNDS, THEIR PREPARATION AND USE AS ANTIBACTERIAL AGENTS | MRPL21, MRPL19, MRPL12 | LMNA 3230/4885ALDH1A1 3395/4885HPGD 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.