Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.37 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.37 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11278799 | 0.83 | MMP1 (0.40) | MMP1MMP2MMP3ALDH1A1KDM4E | |
| 6,7-Dichloro-3-Hydroxy-2-Quinoxalinecarboxylic Acid SCHEMBL4287210 | 0.78 | GRIN2D (0.53) | MMP1MMP2MMP3ALDH1A1MAPT | |
| SCHEMBL9704201 | 0.76 | APEX1 (0.39) | MMP1MMP2MMP3KDM4EGLP1R | |
| SCHEMBL9705662 | 0.72 | RAB9A (0.44) | ALDH1A1KDM4EMAPTGAANPC1 | |
| SCHEMBL2552563 | 0.72 | GLP1R (0.66) | ALDH1A1KDM4EMAPTGLP1RGAA | |
| 2,3-Dihydroxy-6,7-Dichloroquinoxaline SCHEMBL1259521 | 0.72 | MMP1 (0.50) | MMP1MMP2MMP3ALDH1A1GLP1R | |
| SCHEMBL9871154 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL30843193 | 0.66 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTLMNAGAA | |
| SCHEMBL6108034 | 0.63 | GAA (0.48) | MMP1MMP2MMP3ALDH1A1KDM4E | |
| SCHEMBL12583519 | 0.63 | HRH4 (0.44) | MMP1MMP2MMP3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011122815-A2 | NOVEL QUINOXALINE DERIVATIVES | DONG-A PHARM.CO.,LTD. (KR) | 2011-10-06 | — | — | WO | disclosed |