Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.33 |
| ▸ | HPGD | P15428 | 6/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.33 |
| ▸ | CASP1 | P29466 | 3/20 | 0.33 |
| ▸ | CASP7 | P55210 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25485790 | 0.89 | KDM4E (0.36) | ALDH1A1CYP1A2HPGDKDM4EMEN1 | |
| SCHEMBL25485000 | 0.88 | ALDH1A1 (0.34) | ALOX15ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL25484668 | 0.87 | ALOX15 (0.33) | ALOX15ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL25490262 | 0.84 | PSMB8 (0.37) | ALOX15ALDH1A1HSD17B10CYP1A2HPGD | |
| SCHEMBL25484778 | 0.83 | PIM1 (0.39) | ALOX15ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL25485265 | 0.81 | ADORA2A (0.42) | ALOX15ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL25490978 | 0.80 | ALOX15 (0.31) | ALOX15ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL25485507 | 0.77 | PRKDC (0.36) | ALOX15ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL25485263 | 0.75 | ALOX5 (0.37) | ALOX15ALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL20277136 | 0.75 | ALOX5 (0.47) | ALDH1A1HSD17B10CYP1A2CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078812-A1 | BENZOFURO[3,2-D]PYRIMIDINO-2,4-DICARBONITRIL DERIVATIVES AND SIMILAR COMPOUNDS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2023-05-11 | — | — | WO | disclosed |