Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25485790 | 0.86 | KDM4E (0.36) | SMN1; SMN2ADORA2AALDH1A1KDM4ECYP2A6 | |
| SCHEMBL25484667 | 0.84 | ALOX15 (0.34) | ALOX15LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL25490260 | 0.83 | ALDH1A1 (0.38) | PSMB8ALOX15SMN1; SMN2LMNAADORA2A | |
| SCHEMBL25484668 | 0.80 | ALOX15 (0.33) | ALOX15ADORA2AALDH1A1KDM4EHPGD | |
| SCHEMBL25491283 | 0.80 | HSD17B10 (0.37) | HPGDHSD17B10KMT2A | |
| SCHEMBL25485000 | 0.78 | ALDH1A1 (0.34) | ALOX15SMN1; SMN2ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL25178518 | 0.75 | ADORA2A (0.49) | ALOX15SMN1; SMN2LMNAADORA2AALDH1A1 | |
| SCHEMBL9227645 | 0.72 | ADORA2A (0.43) | PSMB8ALOX15SMN1; SMN2ADORA2AALDH1A1 | |
| SCHEMBL22652363 | 0.70 | L3MBTL1 (0.37) | ALOX15SMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL25490426 | 0.68 | ALOX5 (0.40) | PSMB8ALOX15SMN1; SMN2ADORA2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078812-A1 | BENZOFURO[3,2-D]PYRIMIDINO-2,4-DICARBONITRIL DERIVATIVES AND SIMILAR COMPOUNDS FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2023-05-11 | — | — | WO | disclosed |