Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.45 |
| ▸ | FAAH | O00519 | 8/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20567198 | 0.91 | MGLL (0.55) | MGLLFAAH | |
| SCHEMBL30302141 | 0.91 | MGLL (0.55) | MGLLFAAH | |
| SCHEMBL25487279 | 0.90 | MGLL (0.54) | MGLLFAAH | |
| SCHEMBL25829826 | 0.90 | MGLL (0.47) | MGLLFAAH | |
| SCHEMBL25487292 | 0.87 | MGLL (0.34) | MGLLGPR119HCRTR1HCRTR2 | |
| SCHEMBL25487286 | 0.85 | GPR119 (0.43) | MGLLGPR119HCRTR1HCRTR2 | |
| SCHEMBL20566604 | 0.81 | MGLL (0.67) | MGLLFAAH | |
| SCHEMBL25487179 | 0.81 | MGLL (0.51) | MGLLFAAH | |
| SCHEMBL23015503 | 0.78 | MGLL (0.41) | MGLLFAAHGPR119HCRTR1HCRTR2 | |
| SCHEMBL20566947 | 0.76 | MGLL (0.46) | MGLLGPR119HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219897-A1 | PYRAZOLE MAGL INHIBITORS | H. LUNDBECK A/S (DK) | 2023-07-13 | — | — | US | disclosed |
| US-11655217-B2 | Pyrazole MAGL inhibitors | H. LUNDBECK A/S (DK) | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219897-A1 | PYRAZOLE MAGL INHIBITORS | MGLL, PNLIP, LPL | MGLL 1/4885FAAH 33/4885GPR119 308/4885 |
| US-11655217-B2 | Pyrazole MAGL inhibitors | MGLL, PNLIP, LPL | MGLL 1/4885FAAH 32/4885GPR119 353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.