Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 8/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6278630 | 0.83 | ATP1A1 (0.42) | SLC6A4SLC6A3SLC6A2ADRB2FFAR2 | |
| SCHEMBL135747 | 0.82 | SLC6A4 (0.43) | SLC6A4SLC6A3SLC6A2ADRB2FFAR2 | |
| SCHEMBL24528911 | 0.80 | KMT2A (0.39) | SLC6A4SLC6A3SLC6A2TAAR1 | |
| SCHEMBL436301 | 0.79 | UTS2R (0.40) | SLC6A4SLC6A3SLC6A2ADRB2FFAR2 | |
| SCHEMBL5320420 | 0.79 | UTS2R (0.42) | SLC6A4SLC6A3SLC6A2FFAR2UTS2R | |
| SCHEMBL28338266 | 0.79 | GAA (0.45) | SLC6A4SLC6A3SLC6A2ADRB2FFAR2 | |
| SCHEMBL172552 | 0.79 | ALDH1A1 (0.49) | SLC6A4SLC6A3SLC6A2TSHRTAAR1 | |
| SCHEMBL13075028 | 0.79 | ALDH1A1 (0.49) | SLC6A4SLC6A3SLC6A2TSHRTAAR1 | |
| SCHEMBL172587 | 0.79 | ALDH1A1 (0.49) | SLC6A4SLC6A3SLC6A2TSHRTAAR1 | |
| SCHEMBL6032980 | 0.78 | ADRB2 (0.40) | SLC6A4SLC6A3SLC6A2ADRB2FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086799-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023086800-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| WO-2023086801-A1 | HETEROCYCLIC COMPOUNDS AS TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2 AGONISTS AND METHODS OF USE | VIGIL NEUROSCIENCE, INC. (US) | 2023-05-19 | — | — | WO | disclosed |