SCHEMBL2548831

SCHEMBL2548831

CC(=O)c1cccc(/C(C)=N/c2c(C)cccc2C)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
KDM4E B2RXH2 4/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
ACMSD Q8TDX5 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 3/20 0.38
GRIN2D O15399 2/20 0.37
GRIN3B O60391 2/20 0.37
GRIN1 Q05586 2/20 0.37
GRIN2A Q12879 2/20 0.37
GRIN2B Q13224 2/20 0.37
GRIN2C Q14957 2/20 0.37
GRIN3A Q8TCU5 2/20 0.37
SIGMAR1 Q99720 2/20 0.37
HSP90AA1 P07900 2/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
P2RX7 Q99572 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2548834 1.00 CYP1A2 (0.39) CYP1A2KDM4EALOX15TSHRACMSD
SCHEMBL4606192 0.91 GRIN2D (0.42) CYP1A2KDM4EALOX15TSHRACMSD
SCHEMBL4606190 0.91 GRIN2D (0.42) CYP1A2KDM4EALOX15TSHRACMSD
SCHEMBL5693784 0.90 GRIN2D (0.41) CYP1A2KDM4EALOX15TSHRACMSD
SCHEMBL5587834 0.90 GRIN2D (0.41) CYP1A2KDM4EALOX15TSHRACMSD
SCHEMBL30537959 0.90 GRIN2D (0.41) CYP1A2KDM4EALOX15TSHRACMSD
SCHEMBL28632579 0.90 GRIN2D (0.41) CYP1A2KDM4EALOX15TSHRACMSD
SCHEMBL3924090 0.89 ALDH1A1 (0.36) CYP1A2KDM4EALOX15TSHRACMSD
SCHEMBL3924086 0.89 ALDH1A1 (0.36) CYP1A2KDM4EALOX15TSHRACMSD
Hydrochloric Acid SCHEMBL1049917 0.88 GRIN2D (0.40) CYP1A2KDM4EALOX15TSHRACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3517555-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2024-11-27 EP claimed
EP-3517555-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP claimed
US-20190211119-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-07-11 US claimed
US-7056997-B2 Catalyst composition and olefin polymerization using same CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2006-06-06 US claimed
US-20050222350-A1 Catalyst composition and olefin polymerization using same CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2005-10-06 US claimed
US-20030149198-A1 Catalyst composition and olefin polymerization using same CHEVRON PHILLIPS CHEMICAL COMPANY LP 2003-08-07 US claimed
EP-3517555-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2024-11-27 EP disclosed
US-11325994-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2022-05-10 US disclosed
US-20220008347-A1 Self-Assembled Microcapsules With Stimuli-Responsive Organic Ligands THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-01-13 US disclosed
EP-3517555-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP disclosed
US-20190211119-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-07-11 US disclosed
EP-2758413-B1 IRIDIUM CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING (US) 2018-03-07 EP disclosed
US-9545624-B2 Nickel containing hydrosilylation catalysts and compositions containing the catalysts DOW CORNING CORPORATION (US) 2017-01-17 US disclosed
WO-2011126784-A1 IMPROVED ETHYLENE POLYMERIZATION PROCESS AND POLYOLEFIN E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-10-13 WO disclosed
US-7056997-B2 Catalyst composition and olefin polymerization using same CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2006-06-06 US disclosed
US-20050222350-A1 Catalyst composition and olefin polymerization using same CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2005-10-06 US disclosed
US-6911506-B2 Catalyst composition and olefin polymerization using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2005-06-28 US disclosed
EP-1451230-A2 CATALYST COMPOSITION AND OLEFIN POLYMERIZATION USING SAME Chevron Phillips Chemical Company LP (US) 2004-09-01 EP disclosed
US-20030149198-A1 Catalyst composition and olefin polymerization using same CHEVRON PHILLIPS CHEMICAL COMPANY LP 2003-08-07 US disclosed
WO-2003054038-A2 CATALYST COMPOSITION AND OLEFIN POLYMERIZATION USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2003-07-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030149198-A1 Catalyst composition and olefin polymerization using same OXER1, ORC3, OSTC CYP1A2 1440/4885KDM4E 4410/4885ALOX15 82/4885
US-20220008347-A1 Self-Assembled Microcapsules With Stimuli-Responsive Organic Ligands MLEC, MSN, EPHA2 CYP1A2 4008/4885KDM4E 4122/4885ALOX15 707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.