SCHEMBL4606190

SCHEMBL4606190

C/C(=N\c1c(C)cccc1C)c1cccc(/C(C)=N/c2c(C)cccc2C)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 2/20 0.42
GRIN3B O60391 2/20 0.42
GRIN1 Q05586 2/20 0.42
GRIN2A Q12879 2/20 0.42
GRIN2B Q13224 2/20 0.42
GRIN2C Q14957 2/20 0.42
GRIN3A Q8TCU5 2/20 0.42
SIGMAR1 Q99720 2/20 0.42
HSP90AA1 P07900 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ATM Q13315 1/20 0.38
CYP1A2 P05177 1/20 0.36
KDM4E B2RXH2 2/20 0.35
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
ACMSD Q8TDX5 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 2/20 0.34
RAD52 P43351 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4606192 1.00 GRIN2D (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL5693784 0.98 GRIN2D (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL5587834 0.98 GRIN2D (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30537959 0.98 GRIN2D (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL28632579 0.98 GRIN2D (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrochloric Acid SCHEMBL1049917 0.96 GRIN2D (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrochloric Acid SCHEMBL1685878 0.96 GRIN2D (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrochloric Acid SCHEMBL6913575 0.96 GRIN2D (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrochloric Acid SCHEMBL7178276 0.96 GRIN2D (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Hydrochloric Acid SCHEMBL8091207 0.96 SIGMAR1 (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3135697-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2019-08-14 EP claimed
US-10208145-B2 Catalyst component for olefin polymerization, and catalyst containing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-02-19 US claimed
US-20170073441-A1 Catalyst Component For Olefin Polymerization, and Catalyst Containing the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-03-16 US claimed
EP-3135697-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST THEREOF China Petroleum & Chemical Corporation (CN) 2017-03-01 EP claimed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP claimed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP claimed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO claimed
EP-3184172-B1 HYDROSILYLATION IRON CATALYST UNIV KYUSHU NAT UNIV CORP (JP) 2024-09-04 EP disclosed
WO-2023112847-A1 ORGANOSILOXANE-BASED HYDROGEN STORAGE COMPOSITION 国立大学法人東京大学 2023-06-22 WO disclosed
US-20220008347-A1 Self-Assembled Microcapsules With Stimuli-Responsive Organic Ligands THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-01-13 US disclosed
EP-2797862-B1 OLEFIN OLIGOMERIZATION METHODS CHEVRON PHILLIPS CHEMICAL CO LP (US) 2021-04-07 EP disclosed
EP-3135697-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2019-08-14 EP disclosed
US-10239896-B2 Hydrosilylation iron catalyst KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2019-03-26 US disclosed
EP-1320537-A1 CR COMPLEXES AND THEIR USE FOR THE POLYMERIZATION OF ALPHA-OLEFINS Université de Liège (BE) 2003-06-25 EP disclosed
US-20030069128-A1 Multi-dentate late transition metal catalyst complexes and polymerization methods using those complexes EXXONMOBIL RESEARCH & ENGINEERING COMPANY 2003-04-10 US disclosed
WO-2003020778-A1 MULTI-DENTATE LATE TRANSITION METAL CATALYST COMPLEXES AND POLYMERIZATION METHODS USING THOSE COMPLEXES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2003-03-13 WO disclosed
US-6479601-B1 Transition metal catalysts for diene polymerizations THE GOODYEAR TIRE & RUBBER COMPANY 2002-11-12 US disclosed
WO-2002022628-A1 CR COMPLEXES AND THEIR USE FOR THE POLYMERIZATION OF ALPHA-OLEFINS UNIVERSITE DE LIEGE (BE) 2002-03-21 WO disclosed
EP-1188762-A1 Chromium complexes and their use for the polymerization of alpha-olefins Solvay Polyolefins Europe-Belgium (Société Anonyme) (BE) 2002-03-20 EP disclosed
EP-1059313-A1 Transition metal catalyst component for polymerization, aromatic vinyl compound-olefin copolymer and process for its production by means of the catalyst component DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10239896-B2 Hydrosilylation iron catalyst SLC40A1, FTH1, SFXN1 GRIN2D 3098/4885GRIN3B 2888/4885GRIN1 856/4885
US-20220008347-A1 Self-Assembled Microcapsules With Stimuli-Responsive Organic Ligands MLEC, MSN, EPHA2 GRIN2D 4584/4885GRIN3B 4110/4885GRIN1 4190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.