Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 4/20 | 0.45 |
| ▸ | DNMT3A | Q9Y6K1 | 4/20 | 0.45 |
| ▸ | DNMT3L | Q9UJW3 | 3/20 | 0.45 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30290811 | 0.85 | KCNK3 (0.53) | DNMT1DNMT3ADNMT3LEHMT1SIRT2 | |
| SCHEMBL24010669 | 0.85 | KCNK3 (0.53) | DNMT1DNMT3ADNMT3LEHMT1SIRT2 | |
| SCHEMBL26321817 | 0.74 | ABL1 (0.51) | DNMT1DNMT3ADNMT3LEHMT1KCNK3 | |
| SCHEMBL30287677 | 0.72 | POLB (0.55) | DNMT1DNMT3ADNMT3LNPC1KCNK3 | |
| SCHEMBL30232750 | 0.72 | POLB (0.55) | DNMT1DNMT3ADNMT3LNPC1KCNK3 | |
| SCHEMBL24006110 | 0.72 | POLB (0.55) | DNMT1DNMT3ADNMT3LNPC1KCNK3 | |
| SCHEMBL24003919 | 0.72 | POLB (0.55) | DNMT1DNMT3ADNMT3LNPC1KCNK3 | |
| SCHEMBL25821618 | 0.72 | SIRT2 (0.57) | SIRT2NPC1KCNK3KCNK9POLB | |
| SCHEMBL24010134 | 0.70 | BRAF (0.49) | DNMT1DNMT3ADNMT3LEHMT1KMT2A | |
| SCHEMBL30290823 | 0.70 | BRAF (0.49) | DNMT1DNMT3ADNMT3LEHMT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081854-A1 | AKT3 MODULATORS | GEORGIAMUNE LLC (US) | 2023-05-11 | — | — | WO | disclosed |