Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | AGXT | P21549 | 1/20 | 0.51 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25493334 | 0.94 | CACNA2D1 (0.59) | ADRA2CALDH1A1MAPTTDP1HTR3A | |
| SCHEMBL25493025 | 0.86 | KMT2A (0.56) | ALDH1A1MAPTAGXTCACNA2D1MEN1 | |
| SCHEMBL25492992 | 0.85 | KMT2A (0.55) | ALDH1A1MAPTAGXTCACNA2D1FAAH | |
| SCHEMBL25493024 | 0.84 | HTR3A (0.47) | ADRA2CALDH1A1MAPTTDP1HTR3A | |
| SCHEMBL4928979 | 0.82 | ADRB1 (0.69) | ALDH1A1MAPTHTR3AHTR2CDRD2 | |
| SCHEMBL25493030 | 0.82 | ALDH1A1 (0.54) | ALDH1A1AGXTFAAHMEN1GAA | |
| SCHEMBL1372927 | 0.81 | KCNH2 (0.69) | ADRA2CALDH1A1MAPTHTR3AAGXT | |
| SCHEMBL25493023 | 0.80 | LRRK2 (0.47) | ALDH1A1MAPTTDP1MEN1GAA | |
| SCHEMBL21228565 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPTMEN1GAAHTT | |
| SCHEMBL2599616 | 0.78 | ADRA2C (0.59) | ADRA2CALDH1A1MAPTHTR3AAGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | PIMEDBIO, INC. (KR) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | TYR, TYRO3, TH | ADRA2C 1768/4885ALDH1A1 2031/4885MAPT 3176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.