SCHEMBL2549440

SCHEMBL2549440

Cc1cc(-n2nc3cc(Cl)c(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 2/20 0.55
▸ RAB9A P51151 2/20 0.55
▸ SMN1; SMN2 Q16637 4/20 0.49
▸ ALDH1A1 P00352 4/20 0.49
▸ POLB P06746 2/20 0.49
▸ CA2 P00918 2/20 0.49
▸ TYR P14679 1/20 0.49
▸ HSPA5 P11021 1/20 0.41
▸ CYP2C9 P11712 4/20 0.41
▸ CYP2C19 P33261 4/20 0.41
▸ HIF1A Q16665 3/20 0.41
▸ TP53 P04637 1/20 0.39
▸ LMNA P02545 1/20 0.38
▸ CYP2D6 P10635 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ CA1 P00915 1/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ TDP1 Q9NUW8 3/20 0.33
▸ KDM4E B2RXH2 3/20 0.33
▸ MITF O75030 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bumetrizole SCHEMBL8056551 0.86 NPC1 (0.53) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL8054070 0.86 NPC1 (0.53) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL23734 0.86 NPC1 (0.53) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL8603228 0.86 NPC1 (0.53) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL2398487 0.86 NPC1 (0.53) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL29353083 0.86 NPC1 (0.53) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
SCHEMBL9260723 0.85 NPC1 (0.41) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL9273939 0.85 NPC1 (0.52) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL9301984 0.85 NPC1 (0.52) NPC1RAB9ASMN1; SMN2ALDH1A1POLB
Bumetrizole SCHEMBL10836210 0.85 NPC1 (0.52) NPC1RAB9ASMN1; SMN2ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150132518-A1 CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2015-05-14 — — US claimed
US-8962718-B2 Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-02-24 — — US claimed
US-9988518-B2 Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-06-05 — — US disclosed
EP-2563827-B1 CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2017-06-21 — — EP disclosed
US-20150132518-A1 CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2015-05-14 — — US disclosed
US-8962718-B2 Chlorine-resistant crosslinkable polyolefin compositions and articles made therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-02-24 — — US disclosed
EP-2563827-A1 CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM Momentive Performance Materials Inc. (US) 2013-03-06 — — EP disclosed
WO-2011139635-A1 CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-11-10 — — WO disclosed
US-20110259464-A1 CHLORINE-RESISTANT CROSSLINKABLE POLYOLEFIN COMPOSITIONS AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-10-27 — — US disclosed
EP-0065574-B1 PHOTOSYNTHETIC BACTERIA CULTURE NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1986-05-21 — — EP disclosed
US-4467035-A Cultivation of phototrophic bacteria in the absence of ultraviolet light NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1984-08-21 — — US disclosed
EP-0065574-A1 PHOTOSYNTHETIC BACTERIA CULTURE NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1982-12-01 — — EP disclosed
US-4299886-A WITH POLYSILOXANES DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1981-11-10 — — US disclosed
US-4235043-A Method for cultivating algae and a covering material used therefor Nippon Carbide Kogyo Kabashiki Kaisha (JP) 1980-11-25 — — US disclosed
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