Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22080832 | 0.87 | HSP90AA1 (0.39) | NPC1RAB9AHSP90AA1SMN1; SMN2CYP2C9 | |
| SCHEMBL29349567 | 0.86 | NPC1 (0.41) | NPC1RAB9AHSP90AA1CYP2C9CYP2C19 | |
| SCHEMBL29241 | 0.86 | NPC1 (0.41) | NPC1RAB9AHSP90AA1CYP2C9CYP2C19 | |
| SCHEMBL9266071 | 0.85 | HSP90AA1 (0.38) | NPC1RAB9AHSP90AA1SMN1; SMN2CYP2C9 | |
| SCHEMBL3538222 | 0.85 | HSP90AA1 (0.38) | NPC1RAB9AHSP90AA1SMN1; SMN2CYP2C9 | |
| SCHEMBL2549440 | 0.85 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL712969 | 0.84 | NPC1 (0.38) | NPC1RAB9AHSP90AA1SMN1; SMN2CYP2C9 | |
| SCHEMBL29706577 | 0.84 | NPC1 (0.38) | NPC1RAB9AHSP90AA1SMN1; SMN2CYP2C9 | |
| SCHEMBL29708 | 0.84 | NPC1 (0.49) | NPC1RAB9AHSP90AA1SMN1; SMN2CYP2C9 | |
| SCHEMBL22080762 | 0.84 | HSP90AA1 (0.39) | NPC1RAB9AHSP90AA1SMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220017527-A1 | NOVEL PROCEDURE FOR THE FORMATION OF 2H-BENZOTRIAZOLE BODIES AND CONGENERS | BASF SE (DE) | 2022-01-20 | — | — | US | disclosed |
| WO-2020114936-A1 | NOVEL PROCEDURE FOR THE FORMATION OF 2H-BENZOTRIAZOLE BODIES AND CONGENERS | BASF SE (DE) | 2020-06-11 | — | — | WO | disclosed |
| US-5410071-A | Sulfiding with a thiophenolic compound or a thiophenolate in a polar solvent to form a stabilizers for polyphenylene sulfide against UV radiation | PHILLIPS PETROLEUM COMPANY (US) | 1995-04-25 | — | — | US | disclosed |
| US-5319091-A | Contacting sulfur-containing aromatic compound with hydroxyphenylbenzotriazole derivative in presence of polar organic compound, oxidizing formed aryl sulfide derivative to sulfone, sulfoxide or mixtures | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0599269-A1 | Compositions comprising sulfur-containing derivatives of hydroxyphenylbenzotriazole and process therefor | PHILLIPS PETROLEUM COMPANY (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5274015-A | And a polyarylene sulfide polymer | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-28 | — | — | US | disclosed |
| US-5268450-A | Reating sodium hydrosulfide with a sulfur containing hydroxyphenylbenztriazole | PHILLIPS PETROLEUM COMPANY (US) | 1993-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220017527-A1 | NOVEL PROCEDURE FOR THE FORMATION OF 2H-BENZOTRIAZOLE BODIES AND CONGENERS | GABBR1, GABBR2, SULT2A1 | NPC1 2446/4885RAB9A 4723/4885HSP90AA1 2658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.