Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL2126950 | 0.89 | KMT2A (0.38) | HSD17B10GAAKMT2AHTTSMN1; SMN2 | |
| SCHEMBL1727434 | 0.88 | GAA (0.38) | HSD17B10GAAKMT2ASMN1; SMN2POLB | |
| SCHEMBL8472148 | 0.85 | GAA (0.37) | HSD17B10GAAKMT2ATSHRPOLB | |
| SCHEMBL30823619 | 0.80 | GAA (0.41) | HSD17B10GAAKMT2ATSHRPOLB | |
| SCHEMBL1180196 | 0.80 | GAA (0.41) | HSD17B10GAAKMT2ATSHRPOLB | |
| SCHEMBL15311994 | 0.79 | CA2 (0.39) | HSD17B10GAAKMT2ATSHRPOLB | |
| Pyridine SCHEMBL11037587 | 0.79 | KMT2A (0.51) | HSD17B10GAAKMT2AHTTSMN1; SMN2 | |
| SCHEMBL8470871 | 0.78 | CA2 (0.36) | HSD17B10GAAKMT2AHTTTSHR | |
| SCHEMBL5718625 | 0.77 | GAA (0.39) | HSD17B10GAAKMT2AHTTTSHR | |
| SCHEMBL816601 | 0.77 | GAA (0.39) | HSD17B10GAAKMT2ATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110262548-A1 | NOVEL PROSTAGLANDIN E1 DERIVATIVE AND NANOPARTICLE HAVING THE SAME ENCAPSULATED THEREIN | LTT BIO-PHARMA CO., LTD. (JP) | 2011-10-27 | — | — | US | disclosed |
| US-5442065-A | Antitumor agents | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1995-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110262548-A1 | NOVEL PROSTAGLANDIN E1 DERIVATIVE AND NANOPARTICLE HAVING THE SAME ENCAPSULATED THEREIN | PTGER1, PTGS1, PTGES | HSD17B10 517/4885GAA 1004/4885KMT2A 3654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.