Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472148 | 0.97 | GAA (0.37) | GAAHSD17B10AMY1ARECQLPOLB | |
| SCHEMBL1180196 | 0.91 | GAA (0.41) | GAAHSD17B10AMY1ARECQLPOLB | |
| SCHEMBL30823619 | 0.91 | GAA (0.41) | GAAHSD17B10AMY1ARECQLPOLB | |
| SCHEMBL15311994 | 0.90 | CA2 (0.39) | GAAHSD17B10AMY1ARECQLPOLB | |
| SCHEMBL8470871 | 0.88 | CA2 (0.36) | GAAHSD17B10AMY1ARECQLPOLB | |
| Pyridine SCHEMBL2549494 | 0.88 | HSD17B10 (0.38) | GAAHSD17B10RECQLPOLBALDH1A1 | |
| SCHEMBL30723203 | 0.87 | GAA (0.39) | GAAHSD17B10AMY1ARECQLPOLB | |
| SCHEMBL5718625 | 0.87 | GAA (0.39) | GAAHSD17B10AMY1ARECQLPOLB | |
| SCHEMBL29975298 | 0.87 | GAA (0.39) | GAAHSD17B10AMY1ARECQLPOLB | |
| SCHEMBL816601 | 0.87 | GAA (0.39) | GAAHSD17B10AMY1ARECQLPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110204543-B | Pyrrolopyridinone bifunctional molecular compound based on Cereblon ligand induced BET degradation | 江苏省中医药研究院 | 2022-03-29 | — | — | CN | disclosed |
| CN-110143961-B | Pyrrolo-pyridone bifunctional molecular compound based on VHL ligand-induced BET degradation | 江苏省中医药研究院 | 2022-03-29 | — | — | CN | disclosed |
| EP-2940007-B1 | TYROSINE DERIVATIVE AND MANUFACTURING METHOD FOR TYROSINE DERIVATIVE | NARD INSTITUTE LTD (JP) | 2017-12-20 | — | — | EP | disclosed |
| EP-2940007-A2 | TYROSINE DERIVATIVE AND MANUFACTURING METHOD FOR TYROSINE DERIVATIVE | Nard Institute, Ltd. (JP) | 2015-11-04 | — | — | EP | disclosed |
| US-8907126-B2 | Tyrosine derivative and method for producing tyrosine derivative | NARD INSTITUTE, LTD. (JP) | 2014-12-09 | — | — | US | disclosed |
| US-20140187814-A1 | TYROSINE DERIVATIVE AND METHOD FOR PRODUCING TYROSINE DERIVATIVE | NARD INSTITUTE, LTD. (JP) | 2014-07-03 | — | — | US | disclosed |
| US-8506930-B2 | Compounds having affinity for amyloid | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| US-8404036-B2 | Water-soluble near-infrared absorbing coloring matters and aqueous inks containing same | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2013-03-26 | — | — | US | disclosed |
| US-8303935-B2 | Alkoxy substituted imidazo[1,2-a]pyridines having affinity for amyloid | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-20120271053-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2012-10-25 | — | — | US | disclosed |
| US-20110123784-A1 | WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2011-05-26 | — | — | US | disclosed |
| US-20100267952-A1 | USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2010-10-21 | — | — | US | disclosed |
| EP-2218463-A1 | USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-18 | — | — | EP | disclosed |
| US-20090252679-A1 | Novel Compound Having Affinity for Amyloid | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2009-10-08 | — | — | US | disclosed |
| EP-2019103-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2009-01-28 | — | — | EP | disclosed |
| CN-101103002-A | 3,4,(5)-substituted tetrahydropyridines | NOVARTIS AG (CH) | 2008-01-09 | — | — | CN | disclosed |
| CN-1250549-C | Indole derivatives and their use as 5-ht2b and 5-ht2c receptor ligands | HOFFMANN LA ROCHE (CH) | 2006-04-12 | — | — | CN | disclosed |
| CN-1483034-A | Indole derivatives and their use as 5-ht2b and 5-ht2c receptor ligands | - | 2004-03-17 | — | — | CN | disclosed |
| EP-0682535-A1 | NEW MATERIALS | BIOCOMPATIBLES LIMITED (GB) | 1995-11-22 | — | — | EP | disclosed |
| WO-1994016748-A1 | NEW MATERIALS | BIOCOMPATIBLES LIMITED (GB) | 1994-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140187814-A1 | TYROSINE DERIVATIVE AND METHOD FOR PRODUCING TYROSINE DERIVATIVE | TH, MTNR1A, MTNR1B | GAA 4437/4885HSD17B10 2160/4885AMY1A 4228/4885 |
| US-20110123784-A1 | WATER-SOLUBLE NEAR-INFRARED ABSORBING COLORING MATTERS AND AQUEOUS INKS CONTAINING SAME | IK, RB1, COL1A1 | GAA 2451/4885HSD17B10 2848/4885AMY1A 345/4885 |
| US-20090252679-A1 | Novel Compound Having Affinity for Amyloid | APBA1, SAAL1, SLC43A1 | GAA 1744/4885HSD17B10 3826/4885AMY1A 13/4885 |
| US-20100267952-A1 | USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME | APBA1, APP, SAAL1 | GAA 3005/4885HSD17B10 3437/4885AMY1A 4/4885 |
| US-20120271053-A1 | NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID | APBA1, SAAL1, SLC43A1 | GAA 1744/4885HSD17B10 3826/4885AMY1A 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.