SCHEMBL2549562

SCHEMBL2549562

CC(C)O[Si](OC(C)C)(OC(C)C)C1c2ccccc2-c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
ATM Q13315 1/20 0.38
GPR3 P46089 2/20 0.38
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
TSHR P16473 1/20 0.33
HTR2A P28223 1/20 0.33
SLC6A4 P31645 3/20 0.32
SLC6A3 Q01959 3/20 0.32
SLC6A2 P23975 2/20 0.32
ACHE P22303 2/20 0.32
CHRM2 P08172 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
CHRM1 P11229 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1985428 0.77 GPR3 (0.41) POLBKMT2AMEN1ATMGPR3
SCHEMBL9633179 0.72 GPR3 (0.41) POLBKMT2AMEN1ATMGPR3
SCHEMBL3479971 0.72 ACHE (0.38) POLBGPR3CYP1A2CYP2C19TSHR
SCHEMBL2551833 0.69 ACHE (0.40) POLBKMT2AMEN1GPR3CYP1A2
SCHEMBL6671925 0.69 GPR3 (0.46) POLBKMT2AMEN1ATMGPR3
SCHEMBL30390148 0.69 GPR3 (0.46) POLBKMT2AMEN1ATMGPR3
SCHEMBL5981387 0.69 GPR3 (0.46) POLBKMT2AMEN1ATMGPR3
SCHEMBL5175634 0.69 GPR3 (0.46) POLBKMT2AMEN1ATMGPR3
SCHEMBL1906187 0.68 GPR3 (0.41) POLBKMT2AMEN1ATMGPR3
SCHEMBL9610264 0.68 GPR3 (0.41) POLBKMT2AMEN1ATMGPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2553145-B1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND OY (FI) 2022-09-21 EP disclosed
US-20170200615-A1 ETCH RESISTANT ALUMINA BASED COATINGS PIBOND (ZHEJIANG) NEW MATERIALS CO., LTD (CN) 2017-07-13 US disclosed
US-9564339-B2 Etch resistant alumina based coatings PIBOND OY (FI) 2017-02-07 US disclosed
EP-2239301-B1 SILOXANE RESIN COMPOSITIONS TORAY INDUSTRIES (JP) 2016-04-27 EP disclosed
US-20130143408-A1 ETCH RESISTANT ALUMINA BASED COATINGS SILECS OY (FI) 2013-06-06 US disclosed
US-8389649-B2 Siloxane-based resin composition TORAY INDUSTRIES, INC. (JP) 2013-03-05 US disclosed
EP-2553145-A1 ETCH RESISTANT ALUMINA BASED COATINGS Silecs OY (FI) 2013-02-06 EP disclosed
WO-2011121166-A1 ETCH RESISTANT ALUMINA BASED COATINGS SILECS OY (FI) 2011-10-06 WO disclosed
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2010-12-16 US disclosed
EP-2239301-A1 SILOXANE RESIN COMPOSITIONS Toray Industries, Inc. (JP) 2010-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION ICAM1, ESD, CAD POLB 2477/4885KMT2A 327/4885MEN1 4592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.