⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25495888 | 0.83 | PTPN1 (0.32) | — | |
| SCHEMBL25496001 | 0.83 | — | — | |
| SCHEMBL25495885 | 0.83 | — | — | |
| SCHEMBL25495827 | 0.80 | ADORA3 (0.33) | — | |
| SCHEMBL25495889 | 0.79 | LGALS9 (0.35) | — | |
| SCHEMBL21073968 | 0.78 | — | — | |
| SCHEMBL25495879 | 0.78 | — | — | |
| SCHEMBL25495947 | 0.73 | NNMT (0.32) | — | |
| SCHEMBL25495890 | 0.70 | — | — | |
| SCHEMBL20248695 | 0.70 | PRMT6 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146410-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | JANSSEN BIOTECH INC (US) | 2023-05-11 | — | — | US | disclosed |