SCHEMBL2549659

SCHEMBL2549659

CCC[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 8/20 0.61
▸ NPY1R P25929 3/20 0.60
▸ NPY2R P49146 3/20 0.60
▸ NPY4R P50391 3/20 0.60
▸ CTSC P53634 1/20 0.56
▸ UTS2R Q9UKP6 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16358972 0.93 GHSR (0.61) GHSRCTSCUTS2R
SCHEMBL29442437 0.88 CTSC (0.61) GHSRCTSC
SCHEMBL2543497 0.87 GHSR (0.59) GHSRNPY1RNPY2RNPY4RUTS2R
SCHEMBL31202576 0.87 GHSR (0.66) GHSRNPY1RNPY2RNPY4RUTS2R
SCHEMBL31018677 0.86 GHSR (0.57) GHSRCTSCUTS2R
SCHEMBL30999540 0.86 CCKBR (0.61) GHSR
SCHEMBL29356416 0.84 CTSC (0.67) GHSRNPY1RNPY2RNPY4RCTSC
SCHEMBL31232428 0.84 GHSR (0.52) GHSRNPY1RNPY2RNPY4RCTSC
SCHEMBL25549786 0.84 GHSR (0.55) GHSR
SCHEMBL26444818 0.84 GHSR (0.82) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110263975-A1 FLUORESCENT PROBES HAVING A POLYMERIC BACKBONE GE HEALTHCARE AS (NO) 2011-10-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110263975-A1 FLUORESCENT PROBES HAVING A POLYMERIC BACKBONE CD38, ARFGAP1, ADCYAP1R1 GHSR 3866/4885NPY1R 1692/4885NPY2R 2352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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