SCHEMBL25549786

SCHEMBL25549786

CNC(CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCSC)C(=O)NC(CCCCN)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(N)=O

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 6/20 0.55
▸ PRKACB P22694 1/20 0.55
▸ IL23R Q5VWK5 4/20 0.55
▸ NPBWR1 P48145 1/20 0.51
▸ RXFP1 Q9HBX9 1/20 0.51
▸ CCKBR P32239 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16509098 0.93 GHSR (0.57) GHSRPRKACBIL23RNPBWR1RXFP1
SCHEMBL16508980 0.90 IL23R (0.58) GHSRPRKACBIL23RNPBWR1RXFP1
SCHEMBL15748394 0.89 IL23R (0.57) GHSRPRKACBIL23RRXFP1CCKBR
SCHEMBL16508974 0.89 KISS1R (0.61) GHSRPRKACBIL23RNPBWR1RXFP1
SCHEMBL16508998 0.89 GHSR (0.61) GHSRIL23RCCKBR
SCHEMBL31232428 0.88 GHSR (0.52) GHSRPRKACBIL23RCCKBR
SCHEMBL29483770 0.87 GHSR (0.60) GHSRPRKACBNPBWR1
SCHEMBL29641173 0.87 GHSR (0.60) GHSRPRKACBNPBWR1
SCHEMBL29483769 0.87 GHSR (0.60) GHSRPRKACBNPBWR1
SCHEMBL13881781 0.87 KISS1R (0.50) GHSRPRKACBIL23RRXFP1CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230173084-A1 PEPTIDE-BASED SYNTHETIC CHLORIDE ION TRANSPORTERS TAVANTA THERAPEUTICS HUNGARY INCORPORATED (HU) 2023-06-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230173084-A1 PEPTIDE-BASED SYNTHETIC CHLORIDE ION TRANSPORTERS CFTR, SLC26A3, SLC26A4 GHSR 989/4885PRKACB 3094/4885IL23R 1902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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