SCHEMBL25497034

SCHEMBL25497034

Cc1cc(NC(=O)NC(C)C)ccc1C(C)C

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.52
▸ RECQL P46063 1/20 0.52
▸ ALDH1A1 P00352 2/20 0.50
▸ RAB9A P51151 2/20 0.50
▸ KDM4E B2RXH2 2/20 0.50
▸ HSP90AA1 P07900 1/20 0.50
▸ GAA P10253 1/20 0.50
▸ MAPT P10636 1/20 0.50
▸ NPSR1 Q6W5P4 1/20 0.50
▸ CA12 O43570 2/20 0.49
▸ CA1 P00915 2/20 0.49
▸ CA2 P00918 2/20 0.49
▸ CA9 Q16790 2/20 0.49
▸ HPGD P15428 1/20 0.48
▸ POLB P06746 2/20 0.43
▸ NPC1 O15118 1/20 0.42
▸ NAMPT P43490 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25509852 0.84 CA12 (0.53) TSHRRECQLALDH1A1GAAMAPT
SCHEMBL23292690 0.83 RAB9A (0.57) TSHRALDH1A1RAB9AKDM4EHSP90AA1
SCHEMBL14199943 0.81 GAA (0.56) TSHRALDH1A1RAB9AKDM4EHSP90AA1
SCHEMBL25494268 0.81 RAB9A (0.51) TSHRRECQLALDH1A1RAB9AKDM4E
SCHEMBL25900637 0.80 KMT2A (0.53) RECQLALDH1A1RAB9AKDM4EHSP90AA1
SCHEMBL11693008 0.79 MAPT (0.55) TSHRRECQLALDH1A1RAB9AKDM4E
SCHEMBL13449739 0.78 CA12 (0.70) ALDH1A1RAB9AGAACA12CA1
SCHEMBL25494284 0.77 GAA (0.59) ALDH1A1RAB9AKDM4EHSP90AA1GAA
SCHEMBL10892785 0.77 ALDH1A1 (0.55) TSHRALDH1A1RAB9AKDM4EHSP90AA1
SCHEMBL13652644 0.77 PKM (0.54) TSHRALDH1A1RAB9AKDM4EHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates M6PR, ASGR1, IGF2R TSHR 214/4885RECQL 4621/4885ALDH1A1 3655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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