Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.51 |
| ▸ | BAZ2B | Q9UIF8 | 2/20 | 0.48 |
| ▸ | HTR1B | P28222 | 3/20 | 0.47 |
| ▸ | HTR1D | P28221 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 5/20 | 0.44 |
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657201 | 0.84 | KMT2A (0.64) | SIRT1BAZ2BHTR1BHTR1DKMT2A | |
| SCHEMBL25498044 | 0.83 | VPS4B (0.49) | BAZ2BHTR1BHTR1DKMT2AHTR2A | |
| SCHEMBL20602346 | 0.83 | MAPT (0.57) | SIRT1BAZ2BHTR1BHTR1DKMT2A | |
| SCHEMBL20602005 | 0.82 | HTR1B (0.40) | HTR1BHTR1DKMT2AMEN1HTR1A | |
| SCHEMBL6529419 | 0.81 | HTR1B (0.65) | SIRT1BAZ2BHTR1BHTR1DKMT2A | |
| SCHEMBL7409510 | 0.81 | SIRT1 (0.55) | SIRT1BAZ2BHTR1BHTR1DKMT2A | |
| SCHEMBL6529421 | 0.81 | HTR1B (0.65) | SIRT1BAZ2BHTR1BHTR1DKMT2A | |
| SCHEMBL7417626 | 0.81 | HTR1F (0.55) | SIRT1BAZ2BHTR1BHTR1DKMT2A | |
| SCHEMBL28834665 | 0.81 | HTR1B (0.65) | SIRT1BAZ2BHTR1BHTR1DKMT2A | |
| SCHEMBL25493848 | 0.80 | HTR1D (0.34) | SIRT1HTR1BHTR1DKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | PIMEDBIO, INC. (KR) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | TYR, TYRO3, TH | SIRT1 4454/4885BAZ2B 3346/4885HTR1B 1311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.