SCHEMBL25499747

SCHEMBL25499747

COC[C@H]1O[C@H](O)[C@H](NC(C)=O)[C@@H](O)[C@H]1O

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.49
▸ AMDHD2 Q9Y303 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ THRB P10828 1/20 0.44
▸ LMNA P02545 2/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ CYP2D6 P10635 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ HK1 P19367 3/20 0.41
▸ HK2 P52789 3/20 0.41
▸ LGALS3 P17931 1/20 0.41
▸ KMT2A Q03164 1/20 0.38
▸ CD69 Q07108 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18391246 1.00 MAPK1 (0.49) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL26229737 1.00 MAPK1 (0.49) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL13240509 1.00 MAPK1 (0.49) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL4314010 1.00 MAPK1 (0.49) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL29764270 0.88 MAPK1 (0.47) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL12280200 0.86 MAPK1 (0.46) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL8038552 0.86 MAPK1 (0.48) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL22394176 0.86 MAPK1 (0.48) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL8038560 0.86 MAPK1 (0.48) MAPK1AMDHD2ALDH1A1THRBLMNA
SCHEMBL29764253 0.86 MAPK1 (0.48) MAPK1AMDHD2ALDH1A1THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-07-20 — — US disclosed
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates M6PR, ASGR1, IGF2R MAPK1 2043/4885AMDHD2 208/4885ALDH1A1 3655/4885
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, FCGR3B, FCGR2A MAPK1 3302/4885AMDHD2 2737/4885ALDH1A1 4520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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