⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2008684 | 0.67 | LTA4H (0.37) | — | |
| SCHEMBL4912618 | 0.66 | — | — | |
| SCHEMBL4914695 | 0.62 | — | — | |
| SCHEMBL7587292 | 0.59 | ALDH1A1 (0.31) | — | |
| SCHEMBL4911707 | 0.58 | — | — | |
| SCHEMBL4440111 | 0.55 | MAPT (0.46) | — | |
| SCHEMBL4912167 | 0.54 | AOC1 (0.33) | — | |
| SCHEMBL5173348 | 0.54 | — | — | |
| SCHEMBL1274799 | 0.54 | — | — | |
| SCHEMBL3339569 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170096441-A1 | PHOSPHONATES WITH REDUCED TOXICITY FOR TREATMENT OF VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-04-06 | — | — | US | disclosed |
| CN-102939291-B | Phosphonate ester for the toxicity with reduction for the treatment of of viral infections | 加利福尼亚大学董事会 | 2016-09-07 | — | — | CN | disclosed |
| EP-2558466-A2 | PHOSPHONATES WITH REDUCED TOXICITY FOR TREATMENT OF VIRAL INFECTIONS | The Regents of the University of California (US) | 2013-02-20 | — | — | EP | disclosed |
| CN-102939291-A | Phosphonates with reduced toxicity for treatment of viral infections | UNIV CALIFORNIA | 2013-02-20 | — | — | CN | disclosed |
| WO-2011130557-A2 | PHOSPHONATES WITH REDUCED TOXICITY FOR TREATMENT OF VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-10-20 | — | — | WO | disclosed |