SCHEMBL7587292

SCHEMBL7587292

Nc1cnc(N)n(N)c1=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4912618 0.69
SCHEMBL4914695 0.65
SCHEMBL4911707 0.60
SCHEMBL11489827 0.60 KDM4E (0.33) ALDH1A1
SCHEMBL11479664 0.60 ALDH1A1 (0.35) ALDH1A1
SCHEMBL2550152 0.59
SCHEMBL7029971 0.57 ALDH1A1 (0.55) ALDH1A1
SCHEMBL10505558 0.57
SCHEMBL21393806 0.56 NOS3 (0.40) ALDH1A1
SCHEMBL21363603 0.56 NOS3 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107311939-A A kind of preparation method of substituted pyrimidone derivatives 南京科技职业学院 2017-11-03 CN claimed
EP-1026166-B1 Process for the preparation of folic acid BASF AG (DE) 2002-10-02 EP claimed
US-6348593-B1 REACTING 2,2,3,3-TETRAALKOXYPROPANOL/1-/ WITH TRIAMINOPYRIMIIDONE AND P-AMINOBENZOYL-L-GLUTAMIC ACID; CYCLIZATION BASF AKTIENGESELLSCHAFT (DE) 2002-02-19 US claimed
US-6348593-B1 REACTING 2,2,3,3-TETRAALKOXYPROPANOL/1-/ WITH TRIAMINOPYRIMIIDONE AND P-AMINOBENZOYL-L-GLUTAMIC ACID; CYCLIZATION BASF AKTIENGESELLSCHAFT (DE) 2002-02-19 US disclosed
US-6348593-B1 REACTING 2,2,3,3-TETRAALKOXYPROPANOL/1-/ WITH TRIAMINOPYRIMIIDONE AND P-AMINOBENZOYL-L-GLUTAMIC ACID; CYCLIZATION BASF AKTIENGESELLSCHAFT (DE) 2002-02-19 US disclosed
US-5410056-A Method for the production of folic acid HOFFMAN-LA ROCHE INC. (US) 1995-04-25 US disclosed