Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23848294 | 0.90 | SETD7 (0.43) | OPRM1OPRD1OPRK1LMNAKCNH2 | |
| Hydrochloric Acid SCHEMBL8983767 | 0.89 | SETD7 (0.42) | OPRM1OPRD1OPRK1LMNAKCNH2 | |
| SCHEMBL3662534 | 0.81 | CYP1A1 (0.41) | OPRM1OPRD1OPRK1CES2CES1 | |
| SCHEMBL23848519 | 0.81 | CYP1A1 (0.41) | OPRM1OPRD1OPRK1CES2CES1 | |
| SCHEMBL3662531 | 0.81 | CYP1A1 (0.41) | OPRM1OPRD1OPRK1CES2CES1 | |
| SCHEMBL8316576 | 0.80 | OPRD1 (0.60) | OPRM1OPRD1OPRK1CES2CES1 | |
| SCHEMBL8313311 | 0.79 | OPRM1 (0.50) | OPRM1OPRD1OPRK1LMNAKCNH2 | |
| SCHEMBL3662643 | 0.77 | OPRM1 (0.44) | OPRM1OPRD1OPRK1LMNAKCNH2 | |
| SCHEMBL3662638 | 0.77 | OPRM1 (0.44) | OPRM1OPRD1OPRK1LMNAKCNH2 | |
| SCHEMBL23832799 | 0.77 | OPRD1 (0.44) | OPRM1OPRD1CES2CES1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146127-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | ATUX ISKAY LLC | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230146127-A1 | 3-DIARYLMETHYLENES AND USES THEREOF | MYC, MYCBP, FOXO1 | OPRM1 4274/4885OPRD1 3701/4885OPRK1 3381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.