Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.43 |
| ▸ | CD44 | P16070 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23848294 | 0.88 | SETD7 (0.43) | OPRM1OPRD1OPRK1KCNH2SETD7 | |
| SCHEMBL2457390 | 0.87 | OPRD1 (0.61) | OPRM1OPRD1OPRK1KCNH2SETD7 | |
| Hydrochloric Acid SCHEMBL8983767 | 0.86 | SETD7 (0.42) | OPRM1OPRD1OPRK1KCNH2SETD7 | |
| SCHEMBL3662638 | 0.85 | OPRM1 (0.44) | OPRM1OPRD1OPRK1KCNH2SETD7 | |
| SCHEMBL3662643 | 0.85 | OPRM1 (0.44) | OPRM1OPRD1OPRK1KCNH2SETD7 | |
| Hydrochloric Acid SCHEMBL7647391 | 0.85 | OPRD1 (0.59) | OPRM1OPRD1OPRK1KCNH2SETD7 | |
| Bromide SCHEMBL10598951 | 0.85 | OPRD1 (0.59) | OPRM1OPRD1OPRK1KCNH2SETD7 | |
| SCHEMBL21381596 | 0.82 | LMNA (0.47) | OPRM1OPRD1OPRK1KCNH2SETD7 | |
| SCHEMBL25501915 | 0.79 | OPRM1 (0.42) | OPRM1OPRD1OPRK1KCNH2SETD7 | |
| SCHEMBL9434960 | 0.79 | OPRD1 (0.57) | OPRM1OPRD1OPRK1KCNH2SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |