Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14862769 | 0.98 | CYP2A6 (0.35) | CYP2A6MEN1LMNATHRBBLM | |
| SCHEMBL2555589 | 0.94 | CYP2A6 (0.37) | CYP2A6MEN1LMNATHRBBLM | |
| SCHEMBL2550311 | 0.71 | ABCC1 (0.38) | MEN1LMNAKMT2ATDP1 | |
| SCHEMBL1474805 | 0.67 | — | — | |
| SCHEMBL4458509 | 0.67 | CEL (0.35) | LMNA | |
| SCHEMBL8167373 | 0.67 | LMNA (0.36) | LMNA | |
| SCHEMBL14862766 | 0.67 | MAPK10 (0.40) | MEN1LMNAKMT2ATDP1 | |
| SCHEMBL1419542 | 0.66 | CYP2A6 (0.45) | CYP2A6MEN1LMNATHRBBLM | |
| SCHEMBL21774340 | 0.66 | PTGS1 (0.50) | CYP2A6 | |
| SCHEMBL18825990 | 0.65 | CEL (0.35) | LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011123937-A1 | KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIVERSITY HEALTH NETWORK (CA) | 2011-10-13 | — | — | WO | disclosed |