Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CEL | P19835 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CAMKK1 | Q8N5S9 | 2/20 | 0.32 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18825990 | 0.98 | CEL (0.35) | LMNAALDH1A1NPC1MAPTNFKB1 | |
| SCHEMBL2126610 | 0.92 | HSD17B10 (0.32) | LMNAALDH1A1NPC1MAPTNFKB1 | |
| SCHEMBL4973739 | 0.72 | CA1 (0.37) | — | |
| SCHEMBL4458509 | 0.69 | CEL (0.35) | LMNACELHSP90AA1CAMKK1CAMKK2 | |
| SCHEMBL7324741 | 0.69 | LMNA (0.35) | LMNAMAPTCELCAMKK1CAMKK2 | |
| SCHEMBL8167370 | 0.69 | LMNA (0.42) | LMNAALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL14862769 | 0.69 | CYP2A6 (0.35) | LMNAALDH1A1 | |
| SCHEMBL3558293 | 0.69 | GPR35 (0.36) | ALDH1A1CEL | |
| SCHEMBL4580554 | 0.68 | ALDH1A1 (0.42) | LMNAALDH1A1NPC1MAPTNFKB1 | |
| SCHEMBL13630799 | 0.67 | KDM4E (0.36) | LMNAALDH1A1MAPTRAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473911-B | Formylthiophenes and their use in flavour and fragrance compositions | 国际香料和香精公司 | 2021-10-29 | — | — | CN | disclosed |
| EP-3371291-B1 | FORMYLTHIOPHENES AND THEIR USE IN FLAVOR AND FRAGRANCE COMPOSITIONS | INT FLAVORS & FRAGRANCES INC (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-3371291-B1 | FORMYLTHIOPHENES AND THEIR USE IN FLAVOR AND FRAGRANCE COMPOSITIONS | INT FLAVORS & FRAGRANCES INC (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-3371291-A1 | FORMYLTHIOPHENES AND THEIR USE IN FLAVOR AND FRAGRANCE COMPOSITIONS | International Flavors & Fragrances Inc. (US) | 2018-09-12 | — | — | EP | disclosed |
| CN-108473911-A | Formylthiophenes and their use in flavour and fragrance compositions | 国际香料和香精公司 | 2018-08-31 | — | — | CN | disclosed |
| WO-2017079368-A1 | FORMYLTHIOPHENES AND THEIR USE IN FLAVOR AND FRAGRANCE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-05-11 | — | — | WO | disclosed |
| WO-2017079368-A1 | FORMYLTHIOPHENES AND THEIR USE IN FLAVOR AND FRAGRANCE COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2017-05-11 | — | — | WO | disclosed |
| WO-2000049012-A1 | PROCESS FOR THE PRODUCTION OF CYCLOPENTYL 2-THIENYL KETONE | GREAT LAKES CHEMICAL CORPORATION (US) | 2000-08-24 | — | — | WO | disclosed |
| US-5969159-A | Synthesis of cyclopentyl 2-thienyl ketone tiletamine and tiletamine acid addition salts such as tiletamine hydrochloride | GREAT LAKES CHEMICAL CORPORATION (US) | 1999-10-19 | — | — | US | disclosed |