SCHEMBL25505995

SCHEMBL25505995

CCOC(=O)c1cc2cc(OCCOC)ccc2n1CCOC

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.47
KDM4E B2RXH2 2/20 0.47
GAA P10253 1/20 0.47
TSHR P16473 1/20 0.47
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MAOA P21397 1/20 0.46
HPGD P15428 2/20 0.44
ALDH1A1 P00352 1/20 0.44
KMT2A Q03164 2/20 0.44
NOD2 Q9HC29 1/20 0.44
NOD1 Q9Y239 1/20 0.44
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30041116 1.00 HSD17B10 (0.47) HSD17B10KDM4EGAATSHRCRHBP
SCHEMBL31370713 0.90 L3MBTL1 (0.52) HSD17B10KDM4EHPGDALDH1A1MAPT
SCHEMBL30041072 0.90 L3MBTL1 (0.52) HSD17B10KDM4EHPGDALDH1A1MAPT
SCHEMBL25505997 0.85 NTRK1 (0.53) HSD17B10KDM4ESMN1; SMN2HPGDALDH1A1
SCHEMBL23045682 0.83 KDM4E (0.49) HSD17B10KDM4EGAATSHRCRHBP
SCHEMBL21647437 0.83 KDM4E (0.49) HSD17B10KDM4EGAATSHRCRHBP
SCHEMBL29463272 0.83 KDM4E (0.49) HSD17B10KDM4EGAATSHRCRHBP
SCHEMBL29463255 0.80 KMT2A (0.50) HSD17B10KDM4EGAATSHRCRHBP
SCHEMBL21647472 0.80 KDM4E (0.51) HSD17B10KDM4EGAATSHRCRHBP
SCHEMBL23045605 0.80 KMT2A (0.50) HSD17B10KDM4EGAATSHRCRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775261-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2025-04-08 CN disclosed
CN-115427404-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-12-13 CN disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 US disclosed
CN-115427404-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-12-02 CN disclosed
WO-2021216665-A9 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 HSD17B10 3726/4885KDM4E 1980/4885GAA 1678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.