SCHEMBL25508741

SCHEMBL25508741

c1ccc(-c2ccc(-c3nc(-c4ccc5ccccc5c4)nc(-c4cncc5oc6ccccc6c45)n3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.40
ALDH1A1 P00352 4/20 0.40
HSD17B10 Q99714 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
CYP1A2 P05177 2/20 0.40
TP53 P04637 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP11B1 P15538 4/20 0.38
CYP11B2 P19099 4/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2B6 P20813 1/20 0.38
CYP2C19 P33261 1/20 0.38
CYP17A1 P05093 1/20 0.37
CYP19A1 P11511 1/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
PRKCZ Q05513 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25508744 1.00 KDM4E (0.40) KDM4EALDH1A1HSD17B10SMN1; SMN2CYP1A2
SCHEMBL25508981 0.98 CYP11B1 (0.40) KDM4EALDH1A1HSD17B10SMN1; SMN2CYP1A2
SCHEMBL25508982 0.96 CYP11B1 (0.39) KDM4EALDH1A1HSD17B10SMN1; SMN2CYP1A2
SCHEMBL25509102 0.96 CYP11B1 (0.39) KDM4EALDH1A1HSD17B10SMN1; SMN2CYP1A2
SCHEMBL23946598 0.95 CYP11B1 (0.41) KDM4EALDH1A1HSD17B10SMN1; SMN2CYP1A2
SCHEMBL25509530 0.93 KDM4E (0.39) KDM4EALDH1A1HSD17B10SMN1; SMN2CYP1A2
SCHEMBL25504543 0.93 KDM4E (0.39) KDM4EALDH1A1HSD17B10SMN1; SMN2CYP1A2
SCHEMBL25508740 0.93 CYP11B1 (0.37) KDM4EALDH1A1HSD17B10SMN1; SMN2CYP1A2
SCHEMBL25508410 0.93 ALDH1A1 (0.35) KDM4EALDH1A1HSD17B10SMN1; SMN2CYP1A2
SCHEMBL25508746 0.93 PRKCZ (0.37) KDM4EALDH1A1HSD17B10SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240237518-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-07-11 US disclosed
US-20240237518-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-07-11 US disclosed
US-20240215441-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-06-27 US disclosed
US-20230174544-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-06-08 US disclosed
US-20230174544-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2023-06-08 US disclosed
WO-2023090836-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-05-25 WO disclosed
WO-2023085908-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2023-05-19 WO disclosed
WO-2023085878-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-05-19 WO disclosed
WO-2023085881-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230174544-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CRY2, CYBA, AHR KDM4E 2876/4885ALDH1A1 484/4885HSD17B10 1154/4885
US-20240215441-A1 ORGANIC LIGHT EMITTING DEVICE CRY2, CRY1, AHR KDM4E 3831/4885ALDH1A1 182/4885HSD17B10 876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.