SCHEMBL25509898

SCHEMBL25509898

O=CCN(CC=O)CC(=O)OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.54
▸ MAPK1 P28482 1/20 0.54
▸ L3MBTL1 Q9Y468 1/20 0.54
▸ CA1 P00915 5/20 0.47
▸ CA2 P00918 5/20 0.47
▸ HCAR2 Q8TDS4 1/20 0.46
▸ TDP1 Q9NUW8 2/20 0.46
▸ SLC6A2 P23975 1/20 0.46
▸ SLC6A3 Q01959 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ GLA P06280 1/20 0.45
▸ LMNA P02545 2/20 0.44
▸ CA4 P22748 3/20 0.44
▸ CDC25B P30305 1/20 0.42
▸ MAPT P10636 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ CA12 O43570 1/20 0.41
▸ AKR1B10 O60218 1/20 0.41
▸ AKR1B1 P15121 1/20 0.41
▸ CA6 P23280 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19866307 0.86 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1HCAR2TDP1
SCHEMBL339168 0.83 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1CA1CA2
SCHEMBL17879693 0.81 CA1 (0.66) ALDH1A1MAPK1L3MBTL1CA1CA2
SCHEMBL7571319 0.81 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1CA1CA2
SCHEMBL17879683 0.81 CA1 (0.66) ALDH1A1MAPK1L3MBTL1CA1CA2
SCHEMBL19523332 0.80 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1CA1CA2
SCHEMBL7687643 0.79 ALDH1A1 (0.56) ALDH1A1MAPK1L3MBTL1CA1CA2
SCHEMBL13589983 0.79 CA1 (0.68) ALDH1A1MAPK1L3MBTL1CA1CA2
SCHEMBL3093075 0.79 CA1 (0.68) ALDH1A1MAPK1L3MBTL1CA1CA2
SCHEMBL2562532 0.78 ALDH1A1 (0.63) ALDH1A1MAPK1L3MBTL1HCAR2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212131-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-07-06 — — US disclosed
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-05-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230150980-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 ALDH1A1 1196/4885MAPK1 944/4885L3MBTL1 2494/4885
US-20230212131-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 ALDH1A1 1209/4885MAPK1 844/4885L3MBTL1 2471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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