Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19726788 | 0.89 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL25670561 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL25509898 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL8911820 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL18283191 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL29304528 | 0.83 | LTA4H (0.55) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL6050874 | 0.83 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL8377212 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL14586581 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1MAPTHPGD | |
| SCHEMBL8377215 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220267300-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2022-08-25 | — | — | US | disclosed |
| US-10821186-B2 | Lipids and compositions for the delivery of therapeutics | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-11-03 | — | — | US | disclosed |
| US-20190167800-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2019-06-06 | — | — | US | disclosed |
| US-20180043009-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267300-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | IL1B, IL1A, CASP1 | ALDH1A1 226/4885MAPK1 580/4885L3MBTL1 4200/4885 |
| US-20180043009-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | SGMS2, SGMS1, PHOSPHO1 | ALDH1A1 4388/4885MAPK1 4776/4885L3MBTL1 801/4885 |
| US-10821186-B2 | Lipids and compositions for the delivery of therapeutics | SGMS2, SGMS1, PHOSPHO1 | ALDH1A1 4002/4885MAPK1 4822/4885L3MBTL1 1029/4885 |
| US-20190167800-A1 | NOVEL LIPIDS AND COMPOSITIONS FOR THE DELIVERY OF THERAPEUTICS | SGMS2, SGMS1, PHOSPHO1 | ALDH1A1 4415/4885MAPK1 4788/4885L3MBTL1 1005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.