Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 7/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 6/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24201876 | 0.78 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2PLK1CYP2C9PLAU | |
| SCHEMBL20470769 | 0.77 | AKT1 (0.46) | ALDH1A1SMN1; SMN2CYP2C9MEN1KMT2A | |
| SCHEMBL9722329 | 0.75 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2THRBPLK1THRA | |
| SCHEMBL18868883 | 0.74 | HDAC1 (0.41) | ALDH1A1THRBTHRAMEN1KMT2A | |
| SCHEMBL4899025 | 0.73 | THRB (0.72) | ALDH1A1SMN1; SMN2THRBPLK1THRA | |
| SCHEMBL19750705 | 0.72 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2PLK1CYP2C9PLAU | |
| SCHEMBL20713868 | 0.71 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2PLK1PLAULPL | |
| SCHEMBL8383927 | 0.71 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2PLK1CYP2C9PLAU | |
| SCHEMBL21176949 | 0.71 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2THRBPLK1THRA | |
| SCHEMBL11381140 | 0.71 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2PLK1CYP2C9PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4186529-A1 | IMPROVED ANTIBODY-PAYLOAD CONJUGATES (APCS) PREPARED BY SITE-SPECIFIC CONJUGATION UTILIZING GENETIC CODE EXPANSION | Veraxa Biotech GmbH (DE) | 2023-05-31 | — | — | EP | disclosed |