SCHEMBL9722329

SCHEMBL9722329

C=CC(=C)c1ccc(CC)cc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
THRB P10828 7/20 0.44
PLK1 P53350 1/20 0.44
THRA P10827 6/20 0.42
CYP2C9 P11712 1/20 0.41
CYP2A6 P11509 1/20 0.40
LPL P06858 1/20 0.40
LIPG Q9Y5X9 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 1/20 0.38
TP53 P04637 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
PLAU P00749 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12802088 0.83 THRB (0.65) ALDH1A1THRBPLK1THRALPL
SCHEMBL14144603 0.81 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2THRBPLK1CYP2C9
SCHEMBL12802225 0.80 THRB (0.67) ALDH1A1THRBPLK1THRACYP2C9
SCHEMBL13823852 0.80 PRSS1 (0.45) THRBTHRAMEN1KMT2A
SCHEMBL27892550 0.78 LOXL2 (0.48) THRBTAAR1
SCHEMBL4899025 0.77 THRB (0.72) ALDH1A1SMN1; SMN2THRBPLK1THRA
SCHEMBL6546242 0.77 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2PLK1CYP2A6LPL
SCHEMBL12802110 0.76 BCL2 (0.40) CYP2A6TP53
SCHEMBL25513989 0.75 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2THRBPLK1THRA
SCHEMBL13306977 0.75 ALDH1A1 (0.55) ALDH1A1THRBPLK1THRATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9587042-B2 Process for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, and polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-07 US disclosed
CN-102731722-B For the production of the method for modified conjugated diene polymer, modified conjugated diene polymer and polymer composition SUMITOMO CHEMICAL CO., LTD. (JP) 2016-03-16 CN disclosed
US-8933165-B2 Method for producing modified conjugated diene-based polymer, and method for producing polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-13 US disclosed
US-8835564-B2 Method for producing modified conjugated diene-based polymer, and method for producing polymer composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-16 US disclosed
US-20140088256-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, AND METHOD FOR PRODUCING POLYMER COMPOSITION ZEON CORPORATION (JP) 2014-03-27 US disclosed
US-20140088242-A1 METHOD FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, AND METHOD FOR PRODUCING POLYMER COMPOSITION ZEON CORPORATION (JP) 2014-03-27 US disclosed
CN-102731722-A Process for producing modified conjugated diene-based polymer, modified conjugated diene-based polymer, and polymer composition SUMITOMO CHEMICAL CO 2012-10-17 CN disclosed
US-20120252966-A1 PROCESS FOR PRODUCING MODIFIED CONJUGATED DIENE-BASED POLYMER, MODIFIED CONJUGATED DIENE-BASED POLYMER, AND POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED 2012-10-04 US disclosed
US-5135816-A Radiation-reactive phenylbutadiene multiblock copolymers EXXON CHEMICAL PATENTS INC. (US) 1992-08-04 US disclosed
WO-1992006125-A1 RADIATION-REACTIVE PHENYLBUTADIENE MULTIBLOCK COPOLYMERS EXXON CHEMICAL PATENTS INC. (US) 1992-04-16 WO disclosed
US-5066728-A Radiation-reactive phenylbutadiene multiblock copolymers EXXON CHEMICAL PATENTS INC. (US) 1991-11-19 US disclosed