SCHEMBL25514360

SCHEMBL25514360

CCCNC(CF)CCNC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21870640 0.73
SCHEMBL5371278 0.69 DNM1 (0.43) EPHX1
SCHEMBL14980368 0.68 EPHX1 (0.33) EPHX1
SCHEMBL18727407 0.68 LMNA (0.38)
SCHEMBL28117588 0.67 EPHX1 (0.36) EPHX1
SCHEMBL21695560 0.67 LMNA (0.39) EPHX1
SCHEMBL16649021 0.67 DNM1 (0.42) EPHX1
SCHEMBL24593812 0.66 ACE2 (0.33)
SCHEMBL2334045 0.65 DNM1 (0.46) EPHX1
SCHEMBL9210833 0.65 DNM1 (0.46) EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023086432-A1 PRODRUGS OF NEUROSTEROID ANALOGS AND USES THEREOF EMORY UNIVERSITY (US) 2023-05-19 WO disclosed