Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 3/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 3/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.31 |
| ▸ | VHL | P40337 | 1/20 | 0.31 |
| ▸ | ELOC | Q15369 | 1/20 | 0.31 |
| ▸ | ELOB | Q15370 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7169638 | 0.86 | BAZ2B (0.39) | APOBEC3GBAZ2BBAZ2ABRD4BRD9 | |
| SCHEMBL25515801 | 0.76 | ALDH1A1 (0.35) | KDM4EGAAALDH1A1HPGDKLK7 | |
| SCHEMBL15068342 | 0.76 | TBXAS1 (0.57) | APOBEC3GTBXAS1CYP1A2CYP2C19 | |
| SCHEMBL8916169 | 0.74 | AKR1B1 (0.50) | KDM4EHPGDTBXAS1CYP1A2CYP2C19 | |
| SCHEMBL28084372 | 0.72 | ALDH1A1 (0.34) | KDM4EGAAALDH1A1HPGDTBXAS1 | |
| SCHEMBL27308315 | 0.71 | BCL2 (0.47) | HPGDCYP1A2CYP2C19LMNASMN1; SMN2 | |
| SCHEMBL3460309 | 0.70 | DRD3 (0.46) | APOBEC3GKDM4EGAAALDH1A1HIF1A | |
| SCHEMBL18990413 | 0.69 | ASH1L (0.46) | BAZ2BBAZ2ABRD4BRD9KDM4E | |
| SCHEMBL2315461 | 0.69 | NUDT1 (0.41) | APOBEC3GKDM4EGAALMNATP53 | |
| SCHEMBL3798363 | 0.69 | ALDH1A1 (0.42) | KDM4EGAAALDH1A1HPGDKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081306-A1 | INDOLIZINE COMPOUNDS FOR THE TREATMENT OF MENTAL DISORDERS OR MENTAL ENHANCEMENT | TACTOGEN INC (US) | 2023-05-11 | — | — | WO | disclosed |