Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 0.66 |
| ▸ | CA2 | P00918 | 10/20 | 0.66 |
| ▸ | CA7 | P43166 | 10/20 | 0.66 |
| ▸ | CA13 | Q8N1Q1 | 10/20 | 0.66 |
| ▸ | CA12 | O43570 | 3/20 | 0.66 |
| ▸ | CA9 | Q16790 | 3/20 | 0.66 |
| ▸ | CA3 | P07451 | 2/20 | 0.51 |
| ▸ | CA4 | P22748 | 2/20 | 0.51 |
| ▸ | CA6 | P23280 | 2/20 | 0.51 |
| ▸ | CA5A | P35218 | 2/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18424955 | 0.80 | CA1 (1.00) | CA1CA2CA7CA13CA12 | |
| SCHEMBL25516474 | 0.77 | CA12 (0.64) | CA1CA2CA7CA13CA12 | |
| SCHEMBL15643258 | 0.72 | APEX1 (0.71) | CA1CA2CA7CA13CA12 | |
| SCHEMBL15643251 | 0.72 | MEN1 (0.72) | CA1CA2CA7CA13CA12 | |
| SCHEMBL15643289 | 0.71 | PTGDR2 (0.67) | CA1CA2CA7CA13CA12 | |
| SCHEMBL27894202 | 0.70 | LMNA (0.64) | CA1CA2CA7CA13CA12 | |
| SCHEMBL15643536 | 0.70 | MAPT (0.65) | LMNADRD2TBXA2RALDH1A1MAPT | |
| SCHEMBL15685947 | 0.69 | NPSR1 (0.69) | LMNAALDH1A1MAPTHTT | |
| SCHEMBL15643214 | 0.68 | DRD2 (0.55) | CA1CA2CA7CA13CA12 | |
| SCHEMBL18423867 | 0.68 | CA1 (1.00) | CA1CA2CA7CA13CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230149403-A1 | CARBONIC ANHYDRASE ENZYMES FOR REGULATING MAST CELL HEMATOPOIESIS AND TYPE 2 INFLAMMATION | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230149403-A1 | CARBONIC ANHYDRASE ENZYMES FOR REGULATING MAST CELL HEMATOPOIESIS AND TYPE 2 INFLAMMATION | CA2, CMA1, CPA3 | CA1 10/4885CA2 1/4885CA7 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.