Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25517710 | 0.87 | CTSK (0.35) | USP1 | |
| SCHEMBL23264385 | 0.77 | PKM (0.36) | USP1PKM | |
| SCHEMBL25517696 | 0.74 | CHRM4 (0.31) | — | |
| SCHEMBL25728875 | 0.73 | USP1 (0.31) | USP1PKM | |
| SCHEMBL25517400 | 0.73 | PKM (0.40) | USP1PKM | |
| SCHEMBL25464083 | 0.73 | PKM (0.30) | PKM | |
| SCHEMBL25463368 | 0.71 | USP1 (0.32) | USP1MAPK7 | |
| SCHEMBL25718997 | 0.71 | CYP1A2 (0.33) | — | |
| SCHEMBL25517399 | 0.71 | SLC9A1 (0.36) | USP1MAPK7 | |
| SCHEMBL25521367 | 0.69 | IRAK4 (0.35) | USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083285-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-19 | — | — | WO | disclosed |