SCHEMBL25516747

SCHEMBL25516747

C[C@H](NC(=O)CCCN)C(=O)OC(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.40
CYP1A2 P05177 1/20 0.37
CAPN1 P07384 1/20 0.36
NPSR1 Q6W5P4 3/20 0.36
RECQL P46063 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
XBP1 P17861 1/20 0.35
FAAH O00519 2/20 0.35
MEN1 O00255 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
DNM1 Q05193 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
POLB P06746 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 3/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31421853 0.85 FAAH (0.47) HRH3CAPN1FAAHMEN1MAPK1
SCHEMBL19245755 0.83 CA1 (0.39) HRH3NPSR1RECQLTDP1XBP1
SCHEMBL18913932 0.83 CA1 (0.39) HRH3NPSR1RECQLTDP1XBP1
SCHEMBL31529223 0.83 FAAH (0.57) FAAHMEN1MAPK1KMT2ADNM1
SCHEMBL7151887 0.83 FAAH (0.57) FAAHMEN1MAPK1KMT2ADNM1
SCHEMBL7098518 0.83 FAAH (0.57) FAAHMEN1MAPK1KMT2ADNM1
SCHEMBL31529071 0.83 FAAH (0.57) FAAHMEN1MAPK1KMT2ADNM1
SCHEMBL7151886 0.83 FAAH (0.57) FAAHMEN1MAPK1KMT2ADNM1
SCHEMBL24630326 0.80 SLC6A5 (0.46) TDP1KMT2APOLB
SCHEMBL24630329 0.80 SLC6A5 (0.46) TDP1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates LYCIA THERAPEUTICS, INC. 2023-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230158155-A1 Cell Surface Receptor Binding Compounds and Conjugates M6PR, ASGR1, IGF2R HRH3 1240/4885CYP1A2 4624/4885CAPN1 2186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.