Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 9/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25517145 | 0.86 | MAOB (0.41) | ADORA3MAOBALDH1A1AHRKDM4E | |
| SCHEMBL25517172 | 0.86 | CA12 (0.42) | ADORA3MAOBCA12CA9ALDH1A1 | |
| SCHEMBL13564012 | 0.83 | MAOB (0.47) | ADORA3MAOBCA12CA9CLK1 | |
| SCHEMBL17427794 | 0.80 | MAOB (0.52) | ADORA3MAOBCA12CA9CLK1 | |
| SCHEMBL18267835 | 0.77 | MAOB (0.49) | ADORA3MAOBCA12CA9CLK1 | |
| SCHEMBL17849335 | 0.77 | MAOB (0.58) | ADORA3MAOBCA12CA9HSD11B1 | |
| SCHEMBL25517167 | 0.76 | MAPT (0.41) | ADORA3CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL13564033 | 0.75 | MAOB (0.54) | MAOBTNKSPARP1TNKS2PARP2 | |
| SCHEMBL26749899 | 0.75 | NQO1 (0.37) | ADORA3MAOBALDH1A1AHRKDM4E | |
| SCHEMBL25517164 | 0.75 | MAOB (0.47) | ADORA3MAOBCA12CA9CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230320191-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| US-11659763-B2 | Metal complexes | MERCK PATENT GMBH | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230320191-A1 | METAL COMPLEXES | IMMT, MCU, SOD1 | ADORA3 3932/4885MAOB 2037/4885CA12 868/4885 |
| US-11659763-B2 | Metal complexes | IMMT, MCU, SOD1 | ADORA3 3932/4885MAOB 2037/4885CA12 868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.