SCHEMBL25518101

SCHEMBL25518101

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nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPID Q08752 1/20 0.42
CAD P27708 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
BIRC2 Q13490 1/20 0.40
SLC7A5 Q01650 1/20 0.40
METAP2 P50579 5/20 0.40
METAP1 P53582 4/20 0.40
CTSD P07339 1/20 0.39
SCN9A Q15858 3/20 0.39
MME P08473 1/20 0.38
GAA P10253 1/20 0.38
ALOX15 P16050 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
LARS1 Q9P2J5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8643638 0.92 PPID (0.49) PPIDCADBIRC2SLC7A5METAP2
SCHEMBL8643634 0.92 PPID (0.49) PPIDCADBIRC2SLC7A5METAP2
SCHEMBL8644895 0.83 METAP2 (0.55) PPIDSLC7A5METAP2METAP1SCN9A
SCHEMBL8644894 0.83 METAP2 (0.55) PPIDSLC7A5METAP2METAP1SCN9A
Hydrochloric Acid SCHEMBL31294486 0.83 L3MBTL1 (0.58) PPIDCADL3MBTL1METAP2METAP1
Hydrochloric Acid SCHEMBL9503002 0.82 METAP2 (0.54) PPIDSLC7A5METAP2METAP1SCN9A
SCHEMBL30420085 0.82 L3MBTL1 (0.47) PPIDCADL3MBTL1BIRC2METAP2
SCHEMBL25512946 0.82 L3MBTL1 (0.47) PPIDCADL3MBTL1BIRC2METAP2
SCHEMBL25518410 0.81 SLC7A5 (0.53) SLC7A5MMELARS1
Hydrochloric Acid SCHEMBL30420185 0.81 L3MBTL1 (0.46) PPIDCADL3MBTL1BIRC2METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230151034-A1 PEPTIDOMIMETIC N5-METHYL-N2-(NONANOYL-L-LEUCYL)-L-GLUTAMINATE DERIVATIVES, TRIAZASPIRO[4.14]NONADECANE DERIVATIVES AND SIMILAR COMPOUNDS AS INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION COCRYSTAL PHARMA, INC. 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230151034-A1 PEPTIDOMIMETIC N5-METHYL-N2-(NONANOYL-L-LEUCYL)-L-GLUTAMINATE DERIVATIVES, TRIAZASPIRO[4.14]NONADECANE DERIVATIVES AND SIMILAR COMPOUNDS AS INHIBITORS OF NOROVIRUS AND CORONAVIRUS REPLICATION ASNS, GLUL, GNMT PPID 2288/4885CAD 3653/4885L3MBTL1 397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.