Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2332202 | 0.82 | CA12 (0.53) | GLAALDH1A1TDP1KDM4EMMP9 | |
| SCHEMBL30565254 | 0.81 | CCR5 (0.49) | CCR5ALDH1A1LMNAAPOBEC3GTDP1 | |
| SCHEMBL4518188 | 0.80 | GLA (0.40) | GLACCR5ALDH1A1LMNANR1H3 | |
| Hydrochloric Acid SCHEMBL30639440 | 0.80 | CCR5 (0.47) | CCR5ALDH1A1LMNAAPOBEC3GTDP1 | |
| SCHEMBL25518493 | 0.79 | GLA (0.60) | GLAALDH1A1LMNATDP1MEN1 | |
| SCHEMBL25516484 | 0.79 | GLA (0.47) | GLACCR5APOBEC3GTDP1KDM4E | |
| SCHEMBL13756104 | 0.78 | GLA (0.47) | GLAALDH1A1LMNATDP1HSD11B1 | |
| SCHEMBL11184672 | 0.78 | CCR5 (0.56) | CCR5ALDH1A1LMNAAPOBEC3GTDP1 | |
| SCHEMBL5191089 | 0.76 | CCR5 (0.59) | CCR5ALDH1A1LMNAAPOBEC3GTDP1 | |
| SCHEMBL25702584 | 0.76 | KMT2A (0.50) | GLAAPOBEC3GTDP1HSD11B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159569-A1 | DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159569-A1 | DUAL HDAC6/PROTEASOME INHIBITORS, AND METHODS OF USE THEREOF | HDAC6, PSMG3, PSMB2 | GLA 1167/4885CCR5 4784/4885ALDH1A1 2269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.