Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30639440 | 0.98 | CCR5 (0.47) | CCR5LMNAMAOAMAOBPYCR1 | |
| SCHEMBL29597888 | 0.84 | GLA (0.53) | LMNAPYCR1SMN1; SMN2KDM4EMMP9 | |
| SCHEMBL31592654 | 0.82 | SIGMAR1 (0.49) | LMNAPYCR1ALDH1A1SMN1; SMN2MMP9 | |
| SCHEMBL22590675 | 0.82 | PYCR1 (0.49) | LMNAMAOAMAOBPYCR1TSHR | |
| SCHEMBL25518489 | 0.81 | GLA (0.50) | CCR5LMNAMAOBALDH1A1APOBEC3G | |
| SCHEMBL29141664 | 0.80 | CA12 (0.44) | LMNAMAOAMAOBPYCR1ALDH1A1 | |
| SCHEMBL16364104 | 0.78 | PYCR1 (0.57) | LMNAPYCR1CYP3A4ALDH1A1BLM | |
| SCHEMBL11184672 | 0.78 | CCR5 (0.56) | CCR5LMNAALDH1A1SMN1; SMN2APOBEC3G | |
| SCHEMBL5191089 | 0.76 | CCR5 (0.59) | CCR5LMNATSHRALDH1A1APOBEC3G | |
| SCHEMBL25702588 | 0.76 | KMT2A (0.50) | LMNAMAOAMAOBPYCR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4486452-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR LASSS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2025-01-08 | — | — | EP | disclosed |
| CN-117164465-A | Phenyl cyclopropylamine compound and preparation method and application thereof | 郑州大学 | 2023-12-05 | — | — | CN | disclosed |
| WO-2023166039-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-09-07 | — | — | WO | disclosed |