Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14291334 | 0.88 | DGAT1 (0.36) | DGAT1PTGS2MMP13 | |
| SCHEMBL25516552 | 0.79 | DGAT1 (0.36) | DGAT1PTGS2 | |
| SCHEMBL25464158 | 0.78 | MMP13 (0.40) | DGAT1PTGS2MMP13 | |
| SCHEMBL23264165 | 0.76 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL23244650 | 0.75 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL25463478 | 0.75 | USP1 (0.33) | DGAT1 | |
| SCHEMBL25517770 | 0.73 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL25522266 | 0.72 | GRIN2B (0.43) | — | |
| SCHEMBL17066956 | 0.71 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL25522141 | 0.71 | GABRA2 (0.34) | DGAT1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083286-A1 | SMALL MOLECULE INHIBITORS OF UBIQUITIN SPECIFIC PROTEASE 1 (USP1) AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-19 | — | — | WO | disclosed |