SCHEMBL25519094

SCHEMBL25519094

COC(=C1C2CC3CC(C2)CC1C3)c1cccc(C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
LMNA P02545 2/20 0.40
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
NPC1 O15118 2/20 0.38
EPHX2 P34913 2/20 0.38
PARP1 P09874 1/20 0.38
KCNK3 O14649 3/20 0.36
KCNK9 Q9NPC2 2/20 0.36
KCNH2 Q12809 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
FAAH O00519 1/20 0.36
POLB P06746 1/20 0.36
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13010957 0.85 RAB9A (0.39) RAB9ASMN1; SMN2LMNAHDAC8HDAC6
SCHEMBL734321 0.85 FAAH (0.43) RAB9ANPC1EPHX2PARP1MEN1
SCHEMBL8058782 0.85 FAAH (0.43) RAB9ANPC1EPHX2PARP1MEN1
SCHEMBL732169 0.84 ALDH1A1 (0.41) RAB9ASMN1; SMN2LMNANPC1EPHX2
SCHEMBL31236475 0.84 MEN1 (0.51) RAB9ASMN1; SMN2NPC1EPHX2PARP1
SCHEMBL7598259 0.84 MEN1 (0.51) RAB9ASMN1; SMN2NPC1EPHX2PARP1
SCHEMBL26304032 0.83 SMN1; SMN2 (0.40) RAB9ASMN1; SMN2LMNAHDAC8HDAC6
SCHEMBL8445464 0.82 EPHX2 (0.34) EPHX2MEN1KMT2AFAAHALDH1A1
SCHEMBL14076757 0.79 HDAC8 (0.35) RAB9ASMN1; SMN2LMNAHDAC8HDAC6
SCHEMBL1041440 0.78 KMT2A (0.41) RAB9ASMN1; SMN2NPC1EPHX2PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11649475-B2 Dioxetane compounds and their use for the detection of microorganisms RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2023-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11649475-B2 Dioxetane compounds and their use for the detection of microorganisms DAXX, LITAF, EDF1 RAB9A 4412/4885SMN1; SMN2 4855/4885LMNA 2015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.