Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25519971 | 0.84 | ALDH1A1 (0.43) | ALDH1A1TSHRGAALMNASMN1; SMN2 | |
| SCHEMBL25519678 | 0.81 | L3MBTL1 (0.39) | ALDH1A1TSHRGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL25519699 | 0.81 | SMN1; SMN2 (0.42) | ALDH1A1TSHRGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL25795157 | 0.78 | MCL1 (0.42) | ALDH1A1TSHRLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL1341155 | 0.75 | SMN1; SMN2 (0.41) | ALDH1A1TSHRGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL7112755 | 0.74 | UBE2N (0.57) | ALDH1A1TSHRGAALMNASMN1; SMN2 | |
| SCHEMBL29451317 | 0.74 | L3MBTL1 (0.42) | ALDH1A1TSHRL3MBTL1TDP1RAB9A | |
| SCHEMBL15040608 | 0.73 | L3MBTL1 (0.68) | ALDH1A1TSHRGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL16712195 | 0.73 | ALDH1A1 (0.49) | ALDH1A1TSHRGAALMNASMN1; SMN2 | |
| SCHEMBL801935 | 0.73 | ALDH1A1 (0.49) | ALDH1A1TSHRGAALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142274-A1 | SUBSTITUTED ARYL COMPOUND | NANJING ZAIMING PHARMACEUTICAL CO., LTD. (CN) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142274-A1 | SUBSTITUTED ARYL COMPOUND | RAD51, FANCI, BLM | ALDH1A1 2893/4885TSHR 3887/4885GAA 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.