SCHEMBL25519699

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1341155	0.93	SMN1; SMN2 (0.41)	SMN1; SMN2TDP1TP53CYP3A4ALOX15
	SCHEMBL25519675	0.81	ALDH1A1 (0.46)	SMN1; SMN2TDP1L3MBTL1ALDH1A1KDM4E
	SCHEMBL25519678	0.79	L3MBTL1 (0.39)	SMN1; SMN2TP53L3MBTL1ALDH1A1TSHR
	SCHEMBL20150187	0.75	CYP3A4 (0.50)	SMN1; SMN2TDP1TP53CYP3A4ALOX15
	SCHEMBL30908409	0.75	CYP3A4 (0.50)	SMN1; SMN2TDP1TP53CYP3A4ALOX15
	SCHEMBL1522533	0.75	ALDH1A1 (0.59)	SMN1; SMN2TDP1TP53CYP3A4ALOX15
	SCHEMBL31251140	0.73	GAA (0.56)	SMN1; SMN2CYP3A4ALOX15FEN1CASP1
	SCHEMBL8776028	0.73	CYP3A4 (0.48)	SMN1; SMN2TDP1TP53CYP3A4ALOX15
	SCHEMBL13380519	0.73	GAA (0.56)	SMN1; SMN2CYP3A4ALOX15FEN1CASP1
	SCHEMBL13379613	0.73	CYP3A4 (0.48)	SMN1; SMN2TDP1TP53CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.